Generation and archiving of GM animal models
services
Service | BCO-TG, Oulu | GM-unit, Helsinki | TCDM, Turku |
Generation of gene modified mouse lines with CRISPR-Cas9 | x | x | x |
Generation of transgenic mouse lines by DNA injection | x | x | x |
Generation of knock-out/knock-in mouse lines using ES cell targeting | x | x | x |
Rat genome editing (CRISPR/Cas) | x | ||
Cryopreservation of GM lines (sperm and embryos) | M | M, R (R embryos) |
M |
Recovery of mouse lines by IVF or embryo transfer | x | x | x |
Shipping and importing GM lines# | x | x | x |
Rederivation of contaminated GM lines by embryo transfer | M | M, R | M |
GM colony management | M | M, R | M |
Cell (embryonic stem cells, induced pluripotent stem cells, mouse feeder cells, cancer cell lines) culture services |
x | x | x |
M=mouse, R=rat
#GM units assist or handle the shipments and import of frozen material. Import and shipment of live mice is organized together with the local laboratory animal centres.